Top 5 Effective Alternatives to Wellbutrin SR in 2025

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In 2025, several alternatives to Wellbutrin SR have emerged for treating major depressive disorder. These options include Remeron, Trazodone, Trintellix, Viibryd, and a combination of Lexapro and Wellbutrin SR. Each alternative offers distinct benefits and potential drawbacks, catering to individuals who may not respond well to first-line treatments. Understanding the pros and cons of these medications can help patients make informed decisions about their mental health care.