ED Medication Comparison: Viagra, Cialis, Levitra & More

When it comes to treating erectile dysfunction, a condition where a man can’t get or keep an erection strong enough for sex. Also known as impotence, it affects nearly half of men over 40 at some point. The good news? Medications like Viagra, the brand name for sildenafil, a PDE5 inhibitor that boosts blood flow to the penis, Cialis, the brand name for tadalafil, which lasts longer than most ED pills, and Levitra, the brand name for vardenafil, known for fast action and fewer stomach issues work well for most men. These aren’t magic pills—they’re science-backed tools that help your body respond to sexual stimulation. But they’re not all the same. Some kick in faster. Others last longer. Some play nicer with food or alcohol. Picking the right one isn’t about which is "best"—it’s about which fits your body and your life.

How do these drugs compare? Viagra usually starts working in 30 to 60 minutes and lasts about 4 to 5 hours. Cialis takes a bit longer to kick in—around 30 minutes—but can last up to 36 hours, which is why some call it the "weekend pill." Levitra works fast, often under 30 minutes, and isn’t as affected by fatty meals as Viagra. Then there’s Sildenafil, the generic version of Viagra, which costs a fraction of the brand name but works the same way. Stendra is another option, with a quick onset and lower risk of side effects like headaches or flushing. And while some turn to herbal supplements, there’s little proof they work reliably—and they can interact dangerously with prescription ED meds.

Side effects matter too. Most men get mild stuff—headache, stuffy nose, upset stomach. But if you’re on nitrates for heart disease, you can’t take any of these pills. That’s not a risk you take lightly. Also, if you have liver or kidney issues, your doctor might adjust your dose. Cost varies wildly. Brand names can cost $70 a pill. Generics? Often under $5. Insurance doesn’t always cover them, so shopping smart saves money without sacrificing safety.

This collection of articles breaks down exactly how these drugs stack up—real comparisons, real side effects, real cost differences. You’ll find guides on how Viagra compares to Cialis, why Levitra might be better for some, and how generics can save you hundreds. No marketing fluff. Just what you need to know to pick the right one—and avoid the ones that could hurt you.

Zenegra (Sildenafil) vs Other ED Meds: In‑Depth Comparison

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A detailed comparison of Zenegra (sildenafil) with top ED alternatives, covering effectiveness, onset, duration, cost, and safety to help you choose the right medication.